Hossein Goodarzi Hosseinabadi

“Development of a multi-component adhesive supramolecular patch with controllable drug-eluting properties”

Hossein holds a PhD in Materials Engineering (Prof. Reza Bagheri, SUT) and accomplished his PhD thesis at Harvard-MIT Division of Health Sciences and Technology, Cambridge, USA (Prof. Ali Khademhosseini). After a startup activity, he received a 2-year postdoc fellowship from the Alexander von Humboldt (AvH) foundation in Germany to realize his proposed research between University of Bayreuth (Prof. Leonid Ionov) and University Medical Center Göttingen (Prof. dr. med. Wolfram-Hubertus Zimmermann). He developed a new class of polyurethane supramolecular inks with multi-modal Mw distribution for scaffold bioprinting and engineered heart myocardium (EHM) development. He was employed as a process development scientist in Repairon GmbH–specialized at manufacturing and commercialization of iPSC-based tissues for human organ repair. In May 2024, Hossein joined TU/e (Prof. dr. dr. Dankers) to hack the NeoHeart study, an open competition funded by ZonMw–the Netherlands organization for health research and development. He creates multi-component supramolecular biomaterials with adjustable mechanical properties and engineered drug release profiles. Myocardial infarction causes partial loss of the heart cells and progressive scar formation till heart failure, a condition with only 50% survival rate after 5-years. The project aims to contribute to development of new polymer chemistries that provide mechanical support when adhered to the infarct area, prevent tissue rupture, and release drugs to stimulate the endogenous repair mechanisms, for patients under recovery after infarction.