“Relief from the burden of heart valve diseases can start with the bio-inspired design of complex molecular systems”
Matilde obtained her MSc degree in Industrial Chemistry from the University of Genova (Italy). Currently she is a PhD candidate at the Eindhoven University of Technology in the group of Supramolecular Biomaterials for Translational Biomedical Science. Matilde is involved in the project “ImaValve – Intelligent Materials for In Situ Heart Valve Tissue Engineering”, funded by the European Union’s Seventh Framework Programme.
In situ heart valve tissue engineering relies on a synthetic prosthesis with the potential to transform into a living heart valve once implanted in the human body. In this framework, Matilde’s research is aimed to the development of an instructive scaffold material for the heart valve substitute, with the specific goal of modulating in situ paracrine signalling among pre-differentiated cells during maturation of the new tissue.